Fig. 3.
Kinetics of B16 tumor growth in ears. Following injection of pLNCX2-luc-B16 or CCR7-luc-B16 cells (1×105 per mouse) into ear skin of WT mice, mice were euthanized, and homogenized ear skin lysates were assessed for luciferase activity, which was converted to total tumor cell numbers using a standard curve. One of three experiments with similar results is shown. In this experiment, the following numbers of mice for each group at each time-point were used: Day 1 (six mice), Day 4 (eight mice), Day 7 (10 mice), Day 11 (10 mice), Day 14 (nine mice). **, P < 0.01; *, P< 0.05.