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. Author manuscript; available in PMC: 2008 Sep 17.
Published in final edited form as: J Proteome Res. 2006 Apr;5(4):1017–1023. doi: 10.1021/pr060016+

Fig. 2.

Fig. 2

KVNSE5DA prevents the potentiation of glutamate activated currents produced by DYN and DYN 2–17 in Xenopus oocytes expressing NR1 and NR2B subunits. Potentiation of glutamate induced currents by DYN is reversibly reduced by co-application of d-KVNSE5DA (100μM) (A). Co-application of either d- (black symbols) or l-KVNSE5DA (white symbols) significantly inhibits the potentiation of glutamate activated currents induced by DYN or DYN 2-17. [* p≤ 0.05, n = 7–11; Student’s t-test] (B). The inhibitory effect of l- and d-KVNSE5DA upon DYN 2–17 is concentration-dependent (C).