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. 2008 May 29;586(Pt 14):3551–3562. doi: 10.1113/jphysiol.2008.153551

Figure 2. IL-6 infusion increase S100A8 and S100A9 mRNA levels in human skeletal muscle tissue, but not plasma calprotectin levels.

Figure 2

A and B, S100A8 (A) or S100A9 (B) mRNA levels in muscle biopsies during a 3 h infusion of recombinant IL-6 (from 0 h to 3 h) in humans (n = 7) or controls (n = 7) as described in Methods. Data are presented as geometric means ± standard error normalized to the 0 h time point. **P < 0.01 versus controls (post hoc t tests, Bonferroni corrected). C and D, IL-6 plasma (C) or calprotectin plasma (D) levels in venous blood samples during a 3 h infusion of recombinant IL-6 (from 0 h to 3 h) in humans (n = 7). Data are presented as means ± standard error. **P < 0.01 versus 0 h (post hoc t tests, Bonferroni corrected).