Figure 4. Calprotectin is released from skeletal muscle tissue following exercise.

A and B, calprotectin plasma levels in arterial blood (A) or calprotectin net release (B) (Fick's principle: plasma flow multiplied with arterial–femoral venous differences) before and after 3 h of two-legged knee extensor exercise endurance exercise (from 0 h to 3 h) (n = 7). Data are presented as means ± standard error for calprotectin plasma levels and as medians with interquartile ranges for calprotectin net release levels. *P < 0.05 versus 0 h, **P < 0.01 versus 0 h, ***P < 0.001 versus 0 h.