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The open times were plotted for the indicated constructs/conditions and the distribution was fitted with a single exponential decay, shown in red. The τ was derived from this fit. A, WT InsP3R-1. B, AA InsP3R-1. C, WT InsP3R-1 following addition of forskolin. D, EE InsP3R-1. The τ derived under these various conditions was unaltered.
