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Effect of PTC124 oral administration on cAMP-stimulated transepithelial chloride currents in intestinal tissues from Cftr−/− hCFTR-G542X, Cftr+/+, and Cftr−/− mice. (Upper) Individual data points from short-circuit current measurements. (Lower) Analysis of the data. P values comparing all data points from treated and untreated mice were calculated with Student's t test. P < 0.05 was considered significant.
