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. 2008 Feb 6;105(6):2163–2168. doi: 10.1073/pnas.0711839105

Fig. 6.

Fig. 6.

5-HT1BR agonist-mediated inhibition of l-DOPA-induced rotations and AIMs in p11 WT versus KO mice. p11 WT and KO mice were treated with 50 mg/kg l-DOPA (i.p.) alone or together with the 5-HT1BR agonist, CP94253 (2.5 mg/kg, i.p.) as indicated. (a and b) Effects of l-DOPA alone (days 1, 7, and 16) or together with CP94253 (days 8 and 15) on contralateral turns in p11 WT mice (filled bars) (a) and p11 KO mice (open bars) (b). (c and d) Effects of l-DOPA alone (day 7) and CP94253+l-DOPA (day 15) on AIMs in p11 WT mice (filled bars) (c) or p11 KO mice (open bars) (d). Data represent means ± SEM for 9–11 animals per group. *, P < 0.05 between indicated treatments; one-way ANOVA, followed by Newman–Keuls test. ##, P < 0.01 between l-DOPA- and CP94253 plus l-DOPA-treated mice; Student's t test.