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. 2008 Jun 26;586(Pt 16):3839–3854. doi: 10.1113/jphysiol.2007.149989

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© 2008 The Authors. Journal compilation © 2008 The Physiological Society

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A, time constants of tail calcium currents in response to voltage steps from +60 mV to different tail potentials after 1.5 ms (squares) or 5 ms prepulses (circles). Filled symbols, currents in the absence of BayK 8644. Open symbols, currents in the presence of 100 nm BayK 8644. B, calcium influx during tail calcium currents under the same conditions. Same symbols as in A. C, the average number of channel openings before deactivation under the same conditions. Same symbols as in A. D, current–voltage relationship in the absence (filled circles) and presence of BayK 8644 (open circles). The lines show the best fits by the equation:
The parameters of the I–V curves are: G_m= 32.0 ± 0.9 and 37.8 ± 0.8 pA mV⁻¹, V_r= 53.3 ± 0.6 and 53.7 ± 0.6 mV, V_½=−21.0 ± 0.4 and −30.7 ± 0.4 mV, V_S= 7.9 ± 0.4 and 7.3 ± 0.4 mV for control and BayK 8644, respectively.

graphic file with name tjp0586-3839-m10.jpg — A, time constants of tail calcium currents in response to voltage steps from +60 mV to different tail potentials after 1.5 ms (squares) or 5 ms prepulses (circles). Filled symbols, currents in the absence of BayK 8644. Open symbols, currents in the presence of 100 nm BayK 8644. B, calcium influx during tail calcium currents under the same conditions. Same symbols as in A. C, the average number of channel openings before deactivation under the same conditions. Same symbols as in A. D, current–voltage relationship in the absence (filled circles) and presence of BayK 8644 (open circles). The lines show the best fits by the equation:
The parameters of the I–V curves are: G_m= 32.0 ± 0.9 and 37.8 ± 0.8 pA mV⁻¹, V_r= 53.3 ± 0.6 and 53.7 ± 0.6 mV, V_½=−21.0 ± 0.4 and −30.7 ± 0.4 mV, V_S= 7.9 ± 0.4 and 7.3 ± 0.4 mV for control and BayK 8644, respectively.