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. Author manuscript; available in PMC: 2008 Sep 17.
Published in final edited form as: J Med Chem. 2005 Aug 11;48(16):5329–5336. doi: 10.1021/jm058213s

Table 5.

Cytotoxicity Evaluation (GI50, M) of Compound 5 and 6 Against Selected Tumor Cell Lines.23

Cell Lines Compound 5 Compound 6
Leukemia
 HL-60(TB) 3.81 × 10−8 6.56 × 10−6
   SR 4.78 × 10−8 6.09 × 10−7
  K-562 2.14 × 10−7 3.98 × 10−7
Colon Cancer
  SW-620 7.83 × 10−8 3.81 × 10−6
Renal cancer
  786-0 > 1.0 × 10−4 8.98 × 10−7