TABLE 4.
Changes in inflammatory cytokine expression
| Cytokine | Sputum sample | HFA-BDP active | HFA-BDP placebo | DPI-BUD active | DPI-BUD placebo |
|---|---|---|---|---|---|
| Interleukin-4 | Early | −3.9 ± 0.7 | 1.1 ± 0.8 | −3.5 ± 0.7 | 1.0 ± 1.0 |
| Late | −3.5 ± 0.6 | 0.0 ± 0.7 | −0.7 ± 0.7 | 1.3 ± 0.5 | |
| Interleukin-5 | Early | −2.4 ± 0.3 | −0.5 ± 1.0 | −4.8 ± 1.3 | −1.7 ± 1.2 |
| Late | −3.1 ± 0.6 | 0.4 ± 0.6 | −0.7 ± 1.1 | −0.6 ± 0.7 |
Changes in the percentage of positive cells with respect to total cells. Values are given as means ± SEM. DPI-BUD Budesonide in a dry powder inhaler; HFA-BDP Hydrofluoroalkane formulation of beclomethasone dipropionate