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. 1987 Feb;61(2):604–606. doi: 10.1128/jvi.61.2.604-606.1987

A mutant of herpes simplex virus type 1 exhibits increased stability of immediate-early (alpha) mRNAs.

A A Oroskar, G S Read
PMCID: PMC253989  PMID: 3027388

Abstract

vhs1 is a herpes simplex virus type 1 mutant defective in the shutoff of both host and alpha polypeptide synthesis. In cycloheximide reversal experiments, alpha mRNAs were significantly more stable in vhs1-infected cells than in cells infected with wild-type virus, whether assayed by in vitro translation or Northern blotting.

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Selected References

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