Table 3.
Characteristic | Sec10ΔC | Sec10CT |
---|---|---|
Morphology | Cells enlarged, frequently unbudded | Hyperpolarized cells |
Actin | Delocalized | Localized |
Vesicle accumulation | Yes | No |
Synthetic lethality | With members of Exocyst | With t-SNARE, Sec1p, and some Exocyst members |
Interaction | With Sec15p | ? |
Sec15 co-overexpression | Recruited to Sec15p patch | Co-suppression of hyperpolarized phenotype |