Table 3.
MisPred analysis of EnsEMBL entries
| EnsEMBL | |||||||||
| Conflict 1 | Number of proteins | Identified as containing an extracellular domain | Percentage | Identified as suspicious by MisPred | Percentage* | False Positives | Percentage* | True errors | Percentage* |
| Homo sapiens | 48403 | 3449 | 7.13% | 277 | 8.03% | ND | ND | ND | ND |
| Mus musculus | 31302 | 2038 | 6.51% | 151 | 7.41% | ND | ND | ND | ND |
| Rattus norvegicus | 33745 | 2390 | 7.08% | 325 | 13.6% | ND | ND | ND | ND |
| Monodelphis domestica | 32690 | 2369 | 7.25% | 661 | 27.9% | ND | ND | ND | ND |
| Gallus gallus | 24168 | 1519 | 6.29% | 413 | 27.19% | ND | ND | ND | ND |
| Xenopus tropicalis | 28324 | 2383 | 8.41% | 931 | 39.07% | ND | ND | ND | ND |
| Fugu rubripes | 22102 | 1612 | 7.29% | 627 | 38.9% | ND | ND | ND | ND |
| Danio rerio | 36065 | 3312 | 9.18% | 1224 | 36.96% | ND | ND | ND | ND |
| Ciona intestinalis | 20000 | 1452 | 7.26% | 670 | 46.14% | ND | ND | ND | ND |
| Caenorhabditis elegans | 26439 | 918 | 3.47% | 117 | 12.75% | ND | ND | ND | ND |
| Drosophila melanogaster | 19789 | 1071 | 5.41% | 120 | 11.2% | ND | ND | ND | ND |
| Conflict 2 | Number of proteins | Identified as containing an extra- and an intracellular domain | Percentage | Identified as suspicious by MisPred | Percentage* | False Positives | Percentage* | True errors | Percentage* |
| Homo sapiens | 48403 | 101 | 0.21% | 18 | 17.82% | 18 | 17.82% | 0 | 0.00% |
| Mus musculus | 31302 | 50 | 0.16% | 4 | 8.00% | 4 | 8.00% | 0 | 0.00% |
| Rattus norvegicus | 33745 | 67 | 0.2% | 12 | 17.91% | 10 | 14.93% | 2 | 2.99% |
| Monodelphis domestica | 32690 | 101 | 0.31% | 25 | 24.75% | 9 | 8.91% | 16 | 15.84% |
| Gallus gallus | 24168 | 45 | 0.19% | 5 | 11.11% | 4 | 8.89% | 1 | 2.22% |
| Xenopus tropicalis | 28324 | 57 | 0.2% | 11 | 19.3% | 5 | 8.77% | 6 | 10.53% |
| Fugu rubripes | 22102 | 58 | 0.26% | 19 | 32.76% | 12 | 20.69% | 7 | 12.07% |
| Danio rerio | 36065 | 75 | 0.21% | 8 | 10.67% | 7 | 9.33% | 1 | 1.33% |
| Ciona intestinalis | 20000 | 29 | 0.15% | 2 | 6.90% | 2 | 6.90% | 0 | 0.00% |
| Caenorhabditis elegans | 26439 | 12 | 0.05% | 1 | 8.33% | 1 | 8.33% | 0 | 0.00% |
| Drosophila melanogaster | 19789 | 16 | 0.08% | 1 | 6.25% | 1 | 6.25% | 0 | 0.00% |
| Conflict 3 | Number of proteins | Identified as suspicious by MisPred | Percentage* | False Positives | Percentage* | True errors | Percentage* | ||
| Homo sapiens | 48403 | 1 | 0.002% | 0 | 0.00% | 1 | 0.002% | ||
| Mus musculus | 31302 | 3 | 0.01% | 0 | 0.00% | 3 | 0.01% | ||
| Rattus norvegicus | 33745 | 3 | 0.01% | 0 | 0.00% | 3 | 0.01% | ||
| Monodelphis domestica | 32690 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | ||
| Gallus gallus | 24168 | 1 | 0.004% | 0 | 0.00% | 1 | 0.004% | ||
| Xenopus tropicalis | 28324 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | ||
| Fugu rubripes | 22102 | 2 | 0.01% | 0 | 0.00% | 2 | 0.01% | ||
| Danio rerio | 36065 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | ||
| Ciona intestinalis | 20000 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | ||
| Caenorhabditis elegans | 26439 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | ||
| Drosophila melanogaster | 19789 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | ||
| Conflict 4 | Number of proteins | Proteins containing domains suitable for the study of domain integrity | Percentage | Identified as suspicious by MisPred | Percentage* | False Positives | Percentage* | True errors | Percentage* |
| Homo sapiens | 48403 | 16681 | 34.46% | 850 | 5.1% | ND | ND | ND | ND |
| Mus musculus | 31302 | 9955 | 31.80% | 306 | 3.07% | ND | ND | ND | ND |
| Rattus norvegicus | 33745 | 11826 | 35.05% | 474 | 4.01% | ND | ND | ND | ND |
| Monodelphis domestica | 32690 | 11847 | 36.24% | 381 | 3.22% | ND | ND | ND | ND |
| Gallus gallus | 24168 | 6261 | 25.91% | 383 | 6.12% | ND | ND | ND | ND |
| Xenopus tropicalis | 28324 | 6733 | 23.78% | 318 | 4.72% | ND | ND | ND | ND |
| Fugu rubripes | 22102 | 5464 | 24.72% | 278 | 5.09% | ND | ND | ND | ND |
| Danio rerio | 36065 | 9402 | 26.07% | 591 | 6.29% | ND | ND | ND | ND |
| Ciona intestinalis | 20000 | 2114 | 10.57% | 147 | 6.95% | ND | ND | ND | ND |
| Caenorhabditis elegans | 26439 | 3039 | 11.49% | 86 | 2.83% | ND | ND | ND | ND |
| Drosophila melanogaster | 19789 | 3341 | 16.88% | 58 | 1.74% | ND | ND | ND | ND |
| Conflict 5 | Number of proteins | Identified as suspicious by MisPred | Percentage* | False Positives | Percentage* | True errors | Percentage* | ||
| Homo sapiens | 48403 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | ||
| Danio rerio | 36065 | 9 | 0.02% | 7 | 0.02% | 2 | 0.01% | ||
*Values for suspicious, false positive and true positive sequences are expressed as percentage of the proteins relevant for the given conflict.
ND – not determined