Table 2. Results of logistic regression for the outcome of pseudoexfoliation syndrome for each CLU tagging SNP, age, gender, and LOXL1 diplotype.
| Variables |
All controls |
Oldest controls (>73 years) |
||||||
|---|---|---|---|---|---|---|---|---|
| p value (Wald test) | Odds ratio |
95% CI for OR |
p value (Wald test) | Odds ratio |
95% CI for OR |
|||
| Lower | Upper | Lower | Upper | |||||
| Age |
<0.001 |
1.068 |
1.043 |
1.094 |
<0.001 |
0.886 |
0.846 |
0.927 |
| Sex |
0.283 |
0.779 |
0.493 |
1.23 |
0.204 |
0.734 |
0.455 |
1.183 |
| LOXL1 diplotype |
<0.001 |
1.908 |
1.504 |
2.42 |
<0.001 |
1.792 |
1.421 |
2.259 |
|
rs7821500 |
0.152 |
1.05 |
0.982 |
1.123 |
0.199 |
1.047 |
0.976 |
1.122 |
|
rs17466684 |
0.923 |
0.999 |
0.969 |
1.029 |
0.861 |
1.003 |
0.971 |
1.036 |
|
rs2279591 |
0.414 |
1.018 |
0.975 |
1.062 |
0.396 |
1.02 |
0.975 |
1.067 |
|
rs17057444 |
0.178 |
1.176 |
0.929 |
1.488 |
0.06 |
1.324 |
0.989 |
1.774 |
|
rs3087554 |
0.338 |
1.015 |
0.984 |
1.047 |
0.494 |
1.012 |
0.979 |
1.046 |
|
rs7812347 |
0.761 |
0.994 |
0.956 |
1.034 |
0.916 |
0.998 |
0.956 |
1.041 |
|
rs11136000 |
0.855 |
1.003 |
0.97 |
1.037 |
0.85 |
0.997 |
0.961 |
1.033 |
|
rs9331888 |
0.483 |
0.97 |
0.892 |
1.056 |
0.637 |
0.979 |
0.894 |
1.071 |
|
rs9314349 |
0.989 |
1 |
0.968 |
1.032 |
0.655 |
0.992 |
0.96 |
1.026 |
| Constant | <0.001 | 0 | 0.382 | 0.027 | ||||
All variables were added to the model as a block. Significant factors are highlighted in bold. Results are shown for both the whole study and the age-restricted control set.