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. 2008 Oct 3;4(10):e1000205. doi: 10.1371/journal.pgen.1000205

Figure 1. Inactivation of the dE2F family does not block Yki-induced proliferation in actively dividing cells.

Figure 1

Clones of cells of four different genotypes marked with GFP (green) were induced simultaneously with the MARCM technique and allowed to grow for the same period of time. Cells were visualized by staining with DAPI (blue). Population doubling time (DT) is shown for each genotype. Data were collected from 28 clones for wild type, 28 clones for tub>yki, 66 clones for DP−/−, and 33 clones for tub>yki in DP−/−. Average clone areas are 9,206±613 pixels for wild type; 18,491±1,780 pixels for tub>yki; 2,814±279 pixels for DP−/− and 12,909±1,263 pixels for tub>yki in DP−/−. (A) Control clones induced with a wild type FRT42D chromosome. (B) Clones of wild type cells that overexpress yki contain more cells than control in (A). (C) Clones of dDP mutant cells. (D) Clones of dDP mutant cells that overexpress yki contain more cells than clones of dDP mutant cells (C) or control clones (A).