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(A) Effects of 4 hours of pretreatment with PTX (100 ng/ml) on 100 μM baclofen-induced inositol phosphate synthesis in BEAS-2B cells (n = 10). (B) Effects of PLC inhibitor (5 μM U73122) on 100 μM baclofen-induced inositol phosphate synthesis in BEAS-2B cells (n = 11). Data are shown as percentage of basal and represent means ± SEM. *P < 0.05 and ***P < 0.001 compared with basal. #P < 0.05 and **P < 0.01 compared with baclofen.
