TABLE 2.
Final multivariate model combining alleles associated with clearance and persistence with a P value of <0.05 from univariate analysisa
| Allele | OR | 95% CI | P |
|---|---|---|---|
| B*08 | 1.66 | 1.08-2.55 | 0.02 |
| B*44 | 1.81 | 1.25-2.60 | 0.002 |
| A*0301 | 0.47 | 0.30-0.73 | 0.0008 |
| DRB1*1302 | 0.46 | 0.21-1.04 | 0.06 |
a
DRB1*1302 was borderline significant but has previously been associated with HBV clearance; thus, it is presented here in the final model. Alleles considered in the multivariate model include all alleles significant in univariate analysis, specifically, A*0301, DRB1*1302, B*08, B*44, Cw*0501, Cw*1601, DQB1*0201, DRB1*0301.