FIG. 6.
IFN-γ decreases virus RNA levels in the CNS of TMEV-infected H-2q mice. Levels of virus RNA expression at 7, 14, and 21 days after TMEV infection in the brains and spinal cords (SC) of IFN-γ+/+ H-2q mice, IFN-γ+/− H-2q mice, and IFN-γ−/− H-2q mice were analyzed independently. Levels of viral capsid VP2 RNA were quantified with LightCycler PCR. Statistical differences, determined with the Student t test, between the groups are shown with respective P values. Each symbol on the graph represents an individual animal. The levels of expression of GAPDH RNA were consistent among the groups (mean log10 units, 7.19 ± 0.02).