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. 2003 Nov;77(22):12252–12265. doi: 10.1128/JVI.77.22.12252-12265.2003

TABLE 2.

Spinal cord pathologic changes in IFN-γ−/− mice of H-2q haplotype

Day Mice (no. tested) Mean ± SEM score for:
Inflammation
Demyelination
Gray matter White matter
7 IFN-γ−/− (5) 7.8 ± 3.7 3.1 ± 2.1 0.0 ± 0.0
IFN-γ+/− (6) 6.4 ± 3.6 4.0 ± 2.0 0.0 ± 0.0
IFN-γ+/+ (2) 8.6 ± 8.6 7.2 ± 4.9 0.0 ± 0.0
11-17 IFN-γ−/− (16) 24.7 ± 4.6a 3.8 ± 1.8 0.0 ± 0.0
IFN-γ+/− (7) 5.7 ± 1.3 1.6 ± 0.8 0.0 ± 0.0
16 IFN-γ+/+ (7) 0.5 ± 0.3 2.4 ± 1.0 2.0 ± 0.6
21 IFN-γ−/− (10) 6.1 ± 3.4 5.6 ± 1.5 4.1 ± 1.5
IFN-γ+/− (7) 5.4 ± 4.3 4.9 ± 3.0 4.1 ± 2.4
IFN-γ+/+ (14) 0.0 ± 0.0 3.0 ± 1.3 2.6 ± 1.6
a

Significantly different from values for IFN-γ+/− and IFN-γ+/+ mice, as determined by Mann-Whitney rank sum test (P = 0.016 and P = 0.005, respectively).