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Phylogenetic analysis of Rev variants. (A) Neighbor-joining tree of the pony 625 Rev amino acid variants based on p distance. The tree is divided into 2 clades, designated clades A and clade B. The Rev variants highlighted by yellow boxes were biologically assayed for Rev activity. (B) Neighbor-joining tree of the combined pony 524 and pony 625 Rev amino acid variants based on p distance. Solid lines indicate pony 524 variants, and dashed lines indicate pony 625 variants.
