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. 1999 Jul;10(7):2149–2162. doi: 10.1091/mbc.10.7.2149

Figure 11.

Figure 11

Triple MIDAS mutant CMP-D1D2E1 specifically inhibits the formation of endogenous CMP filaments by chondrocytes. Micrographs of immunofluorescent analysis of cultures of CECs, with mAb1H1 to detect CMP (A–D), with a mAb 9E10 to detect a tag of transfected CMP (E–H), and with mAb 3H8 to detect link protein (I–L). (A, E, and I) Chondrocytes with no transfection. (B, F, and J) Chondrocytes transfected with CMP-D1D2E1-RCAS; (C, G, and K) Chondrocytes transfected with CMP-D1-RCAS; (D, H, and L) Chondrocytes transfected with CMP-D1E1-RCAS. Bar, 35 μm.