TABLE 2.
Virus burdens in SCID/ICR mice after peripheral inoculation
Virus | Virus burden (log PFU/g [± SEM])a in:
|
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Serumb | Peritoneum | Heart | Lung | Muscle | Spleen | Liver | Kidney | Adrenal glands | Brain | |
SPYF-MN | 3.2 (0.1) | 2.4 (0.3) | 1.1 (0.1) | 2.4 (0.3) | 2.0 (0.3) | 1.8 (0.4) | 0.62c | 0.50 (0.1) | 3.5 (0.4) | 8.5 (0.4) |
SPYF-E | 3.3 (0.1) | 2.4 (0.1) | 1.5 (0.2) | 2.1 (0.2) | 2.5 (0.1) | 2.0 (0.3) | 0.95 (0.1) | 0.64c | 4.3 (0.3) | 8.0 (0.2) |
SPYF-EIII | 2.7 (0.1) | 2.5 (0.1) | 1.2 (0.2) | 2.0 (0.2) | 2.7 (0.1) | 1.6 (0.0) | 0.65 (0.2) | 0.40c | 4.2 (0.1) | 7.6 (0.2) |
SPYF-EI-II | 2.5c | 1.6 (0.9) | 1.0d | 2.1 (0.7) | 2.9 (0.3) | 3.0c | 0.91 (0.4) | 0.67d | 5.3 (0.5) | 7.5 (0.2) |
Data are titers based on groups of three to six mice, except as noted. Tissues were harvested at the time that individual mice exhibited signs of encephalitis.
Data for serum are given as PFU per milliliter.
n = 2.
n = 1.