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. 2008 Sep 18;118(10):3462–3469. doi: 10.1172/JCI34378

Figure 2. Gestational exposure to methyl donors enhances allergic airway disease in mice.

Figure 2

H&E staining of lung sections obtained from mice subjected in utero to HMD or LMD diet, then immunized and subjected to an OVA challenge. Low magnification of lungs from HMD (A) and LMD (B) mice. Higher magnification of small airways from HMD (C) and LMD (D) mice. Venule with perivascular cuffing from a dam fed HMD (E) or LMD (F) during gestation. Arrow shows multinucleated giant cells. Arteriole with perivascular cuffing from a dam fed HMD (G) and LMD (H) during gestation. Arrows identify margination of inflammatory cells. Original magnification, ×4 (A and B); ×40 (C–H).