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. 2008 Sep 18;118(10):3462–3469. doi: 10.1172/JCI34378

Figure 3. Transgenerational inheritance of diet-associated risk of allergic asthma.

Figure 3

Male F1 progeny were mated with naive females and maintained on RD. F2 progeny were immunized and subjected to an OVA challenge at 6–10 weeks of age. The F2 progeny were kept on RD. F2 adults (HMD, n = 37; LMD, n = 68) demonstrated nonsignificant differences in the (A) concentration of lung lavage eosinophils (P = 0.099), significant differences in the (B) percentage of lung lavage eosinophils (*P = 0.007), (C) and significant differences in serum IgE (†P < 0.001).