Figure 10. Ptc mice with increased Hh activity exhibit increased EMT after BDL.
Liver sections stained with H&E (A and B) or anti-CK (C and D) in representative WT mice (A and C) and Ptc mice (B and D) after 1-week BDL. QRT-PCR of whole liver tissue from Ptc mice (n = 6) and their WT littermates (n = 6) after 1 week of BDL. (E) Vimentin; (F) collagen 1α(I); (G) Tgfb1; (H) Hmga2; (I) Bmp7. Data are shown as mean ± SEM. *P < 0.05 versus WT-BDL; **P < 0.005, †P = 0.08 versus WT-BDL. Original magnification: ×20 (A and B), ×40 (C and D).