FIG. 5.

Summary of the SNV RU5 point mutations. Depicted at the top is the parental SNV/HIV-1 reporter plasmid. White rectangle, SNV LTR; black line, HIV-1 5′ UTR; black rectangle, HIV-1 gag/pol genes; circle, polyadenylation signal. Splice sites are indicated by an asterisk. The bent arrow indicates the RNA start site, which defines the U3/R border. Nucleotide numbers delineating regions A, B, and C are shown in italics above wild-type A, B, and C regions (not drawn to scale). Plasmid names are on the left. Nucleotide numbers correspond to the first mutated nucleotide at each mutation site and the altered sequence. Lines indicate unchanged sequence. “X” indicates deleted nucleotides.