TABLE 1.

Correlation coefficients obtained by Spearman rank correlation analysis between various parameters of the growth curves and the percentages of growth estimated for each drug concentration after 24 h (R. oryzae), 48 h (A. fumigatus), and 72 h (S. prolificans) of incubation^a

Species	Drug	Result for growth curve parameterc
		Tlag (h)	S (OD/ min)	Smax (ODX/ min)	AUC (ODX/ min)	ΔOD/ min	Mean ΔOD/ min	ODmax
A. fumigatus	TB	−0.99	0.96	0.92	0.82	0.97	0.97	0.90
	IT	−0.93	0.82	0.82	0.72	0.82	0.82	0.82
	AB	−0.91	0.87	0.87	0.87	0.87	0.87	0.87
R. oryzae	TB	NCa	NC	NC	NC	NC	NC	NC
	IT	−0.89	0.86	0.87	0.87	0.77	0.88	0.82
	AB	−0.98	0.86	0.87	0.86	0.84	0.87	0.83
S. prolificans	TB	−0.95	0.94	0.92	0.91	0.94	0.94	0.94
	IT	NC	NC	NC	NC	NC	NC	NC
	AB	−0.86	0.85	0.86	0.81	0.86	0.86	0.86

^aNC, not calculated.

^bAll coefficients were statistically significant (P < 0.01).

^cS, slope of the growth curve; S_max, maximal slope; AUC, area under the concentration-time curve.