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. 2008 Aug 28;27(18):2444–2456. doi: 10.1038/emboj.2008.164

Figure 8.

Figure 8

Evolution of protein prenylation. Transition 1 represents expansion of the lipid-binding site of the ancestral FTase. Transition 2 represents invasion of the ancestral GGTase-I by the bifunctional REP/GDI molecule.