Figure 2.

Consecutive sections through MMTV/c-neu mammary carcinoma xenografts showing immunostaining for CD31 (A, B, C) and SMA (A′, B′, C′). Multiple vessels within the cortex (arrowheads in B) bear a covering of SMA-positive cells (arrow in B′), whereas those within the medulla (arrowheads in C) are mainly SMA-negative (positive is marked with arrow in C′). The spatial distribution of SMA accords with the distribution revealed by immunoblotting (D). Scale bars = 200 μm (A, A′) and 50 μm (B, B′, C, C′) presented in the right lower corner of (A′) and (C′) accordingly.