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. Author manuscript; available in PMC: 2009 Sep 1.
Published in final edited form as: J Comp Neurol. 2008 Sep 1;510(1):47–67. doi: 10.1002/cne.21773

Fig. 7. SynCAM 1–4 in situ hybridization in the main and accessory olfactory bulbs at P15 (A, B, E, F, I, J, M, N) and adult (C, D, G, H, K, L, O, P).

Fig. 7

A. At P15, SynCAM 1 is expressed in the mitral and tufted cells of both the main (OB) and accessory (AOB) olfactory bulbs. Expression is also seen in the granule and deep juxtaglomerular cells. B. Enlarged panel (as indicated by the box in A) showing expression of SynCAM 1 in the different layers of the OB at P15. C. In the adult, SynCAM 1 expression was similar to that at P15, with expression also seen in periglomerular cells. D. Enlarged image of SynCAM 1 expression in adult OB. E. At P15, SynCAM 2 is predominantly expressed in mitral cells of the main olfactory bulb, with significantly weaker expression observed in the accessory olfactory bulb. F. Magnified view of SynCAM 2 expression at P15. G. In the adult olfactory bulb, nearly all cell populations appear to express SynCAM 2 at relatively uniform levels. H. Enlarged image of SynCAM 2 expression in adult OB. I. At P15, SynCAM 3 expression is strongest in the mitral cells of both the main and accessory olfactory bulbs. Faint expression is seen in other cell types. J. Magnified view of SynCAM 3 expression in the OB at P15. K. In the adult, SynCAM 3 expression remains strong and relatively uniform in the mitral and tufted cells of the main olfactory bulb. Granule cells demonstrate a relative increase in signal as compared to P15. L. Magnified panel of adult SynCAM 3 expression in the OB. M. At P15, strongest expression of SynCAM 4 was seen superficially in the periglomerular cells and olfactory ensheathing cells, with other cell types also showing expression. N. Enlarged image of SynCAM 4 expression in the OB at P15. O. In the adult, the pattern of SynCAM 4 expression was similar to that at P15. P. Magnified view of adult SynCAM 4 OB expression. Sections were obtained in a sagittal plane that was relatively medial. OB, main olfactory bulb; AOB, accessory olfactory bulb; ONL, olfactory nerve layer; GL, glomerular layer; EPL, external plexiform layer; MCL, mitral cell body layer; IPL, internal plexiform layer; GCL, granule cell layer. Scale bars = 100 µm (in M, O), 30 µm (in N, P) apply to the respective columns of panels.