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. 2008 Jun 25;295(3):C611–C623. doi: 10.1152/ajpcell.00435.2007

Fig. 2.

Fig. 2.

Stimulation of NFATc3 nuclear translocation in UBSM. A: example micrographs showing the subcellular distribution pattern of NFATc3 under basal conditions and after stimulation with endothelin-1 (ET-1). B: treatment with either ET-1 or platelet-derived growth factor (PDGF) led to a significant increase in NFATc3 nuclear localization compared with basal conditions (*P < 0.05; c = number of cells analyzed). Treatment with FK506 and cyclosporine A (CsA, 1 μM; 30 min) before the addition of the PDGF or ET-1 blocked NFATc3 nuclear translocation.