Fig. 9.
Molecular and electrophysiological evidence for elevated KV2.1 expression in NFATc3-null mice. There was no significant difference in the steady-state activation curves (A) or activation time constants (B) between UBSM myocytes obtained from wild-type and NFATc3-null mice (P < 0.05). C: UBSM tissue from wild-type and NFATc3-null mice was probed for KV2.1 and β-actin mRNA expression. D: comparison of the averaged ratios of KV2.1:β-actin in UBSM tissues indicates that the UBSM from NFATc3-null mice contained significantly higher levels of mRNA for KV2.1 than did UBSM tissues from wild-type mice (D) (*P < 0.05; n = 3 animals each).