Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Acute inhibition (30 min) of glycogen synthase kinase-3 (GSK-3) activity with lithium chloride (20 mM) or SB-216763 (10 μM) caused increased [3H]-2-deoxy-glucose (2-DOG) uptake in A7r5 cells (*P < 0.05 vs. control) (A). More chronic GSK-3 inhibition (24 h) induced glucose transporter type 1 (GLUT1) protein expression (n = 6, *P < 0.05 vs. control) (B) as well as 2-DOG uptake (n = 8, **P < 0.01) (C).
