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Structures of human γD-crystallin and its circular permutant. (A) Structure of human γD-crystallin (PDB ID: 1HK0) is shown by specifying four Greek-key motifs (Nth-I, Cth-I, Nth-II, Cth-II) with different colors. (B) Illustration of the structure of the circular permutant of 1HK0 proposed in this article is shown.
