Table 4.
Difference in health status between genotype groups at baseline
| Healthy at baseline,* % |
P value for trend |
||||
|---|---|---|---|---|---|
| Homo. Major | Heter. | Homo. Minor | Unadjusted | Adj. for Case-Control Stat | |
| FOXO3A1 | 57.41 | 69.48 | 75.51 | 0.01 | 0.065 |
| FOXO3A2 | 57.37 | 69.35 | 77.08 | 0.01 | 0.035 |
| FOXO3A3 | 57.89 | 68.34 | 75.00 | 0.02 | 0.097 |
*″Healthy″ is defined as absence of 6 major chronic diseases (CHD, stroke, cancer, PD, COPD and treated type 2 diabetes; high physical function (can walk one-half mile) and high cognitive function (CASI score > 74).