Table 1.
CTF | Sequence | Solubility, μM |
---|---|---|
Aβ(28–42) | KGAIIGLMVGGVVIA | ≈1 |
Aβ(29–42) | GAIIGLMVGGVVIA | 22 ± 9 |
Aβ(30–42) | AIIGLMVGGVVIA | 11 ± 3 |
Aβ(31–42) | IIGLMVGGVVIA | 62 ± 18 |
Aβ(32–42) | IGLMVGGVVIA | 52 ± 24 |
Aβ(33–42) | GLMVGGVVIA | 134 ± 37 |
Aβ(34–42) | LMVGGVVIA | 132 ± 29 |
Aβ(35–42) | MVGGVVIA | 149 ± 33 |
Aβ(36–42) | VGGVVIA | 134 ± 20 |
Aβ(37–42) | GGVVIA | 143 ± 27 |
Aβ(38–42) | GVVIA | 156 ± 33 |
Aβ(39–42) | VVIA | 141 ± 30 |
The solubility values are average concentrations (±SE) measured by AAA for filtered solutions of each CTF in four to seven independent experiments.