Mapping of Mayven to human chromosome 4. (A)
Genomic DNAs from hamster (h), human (H), and mouse (M) as well as 24
human-rodent somatic cell hybrids (lanes 1–22, X and Y) were digested
with HindIII and probed with a human Mayven cDNA. The
human-specific RFLP bands are indicated by arrowheads and are seen in
the control lane, and in lane 4, which corresponds to human chromosome
4. (B) Mapping of Mayven to 4q21.2-qter. (a) Chromosome 4 and the
somatic cell hybrids are indicated. The chromosome 4 content of each
hybrid is shown as a solid bar. Mayven localization is indicated on the
left. The human–mouse cell hybrid 11687 contains the entire human
chromosome 4. (b) Autoradiography showing the Mayven human-specific
band within the mapping panel. The cell lines from which the DNAs were
extracted are shown above each lane.