Figure 1.

Features of the MPS2 encoded protein. (A) Deduced amino acid sequence of the MPS2 encoded protein. The putative transmembrane segment (residues 311–327) is boxed. Potential Cdc28p phosphorylation sites are indicated in bold letters, and potential destruction box sequences are underlined. The point mutation found in the mps2–1 allele at amino acid 39 is highlighted (E to K). (B) Coiled-coil probability plot. The x-axis is the position of Mps2p amino acids and the y-axis is the probability (p) of being in a coiled-coil using the COILS program (http://www.ch.embnet.org/software/COILS form.html), based on the Lupas algorithm (Lupas et al., 1991).