Abstract
Six patients with pregnancies of 19-31 weeks' duration showing evidence of erythroblastosis fetalis were treated with 25 fetal intracardiac blood transfusions. Complications related to the procedure occurred on five occasions in three patients. In two of the six patients the fetus died, but it was unlikely that death was related to the intracardiac transfusions.
Fetal intracardiac blood transfusion may result in potentially severe complications but offers an alternative when transfusion cannot be performed into the umbilical cord.
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- Bang J., Bock J. E., Trolle D. Ultrasound-guided fetal intravenous transfusion for severe rhesus haemolytic disease. Br Med J (Clin Res Ed) 1982 Feb 6;284(6313):373–374. doi: 10.1136/bmj.284.6313.373. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Benacerraf B. R., Barss V. A., Saltzman D. H., Greene M. F., Penso C. A., Frigoletto F. D., Jr Acute fetal distress associated with percutaneous umbilical blood sampling. Am J Obstet Gynecol. 1987 May;156(5):1218–1220. doi: 10.1016/0002-9378(87)90148-7. [DOI] [PubMed] [Google Scholar]
- Berkowitz R. L., Chitkara U., Goldberg J. D., Wilkins I., Chervenak F. A., Lynch L. Intrauterine intravascular transfusions for severe red blood cell isoimmunization: ultrasound-guided percutaneous approach. Am J Obstet Gynecol. 1986 Sep;155(3):574–581. doi: 10.1016/0002-9378(86)90282-6. [DOI] [PubMed] [Google Scholar]
- Grannum P. A., Copel J. A., Plaxe S. C., Scioscia A. L., Hobbins J. C. In utero exchange transfusion by direct intravascular injection in severe erythroblastosis fetalis. N Engl J Med. 1986 May 29;314(22):1431–1434. doi: 10.1056/NEJM198605293142207. [DOI] [PubMed] [Google Scholar]
- Nicolaides K. H., Rodeck C. H. In utero resuscitation after cardiac arrest in a fetus. Br Med J (Clin Res Ed) 1984 Mar 24;288(6421):900–901. doi: 10.1136/bmj.288.6421.900. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rodeck C. H., Kemp J. R., Holman C. A., Whitmore D. N., Karnicki J., Austin M. A. Direct intravascular fetal blood transfusion by fetoscopy in severe Rhesus isoimmunisation. Lancet. 1981 Mar 21;1(8221):625–627. doi: 10.1016/s0140-6736(81)91549-x. [DOI] [PubMed] [Google Scholar]
- de Crespigny L. C., Robinson H. P., Quinn M., Doyle L., Ross A., Cauchi M. Ultrasound-guided fetal blood transfusion for severe rhesus isoimmunization. Obstet Gynecol. 1985 Oct;66(4):529–532. [PubMed] [Google Scholar]