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. 2008 Sep 26;283(39):26528–26537. doi: 10.1074/jbc.M804624200

FIGURE 8.

FIGURE 8.

Sequence comparisons. A compares the amino acid sequence of LA5 from 12 species. E180, D196, D200, D203, D206, and E207 are conserved in all species. E208 is conserved in 8 of the 12 B compares the amino acid sequence of human LA5 with the other six LA repeats of human LDLR. D206 E207 are conserved; E180, D196, D200, and D203 are somewhat conserved; while E187 and E208 are conserved between different repeats. Boxed residues are acidic residues that are conserved with human Residue numbering is for human LA5.