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. 2008 Oct;10(10):1049–1056. doi: 10.1593/neo.08626

Table 2.

Comparison of DcR3 Expression Levels and Clinical and Pathologic Features.

Feature All Patients Without Distant Metastasis (M0) With Distant Metastasis (M1)
Low (n = 508, 91%) High (n = 52, 9%) P Low (n = 435, 92%) High (n = 38, 8%) P Low (n = 73, 84%) High (n = 14, 16%) P






n % n % n % n % n % n %
Sex .004 .015 .5
Male 306 55 42 8 253 53 30 6 53 61 12 14
Female 202 36 10 2 182 39 8 2 20 23 2 2
Age at surgery 1 .9
<65 years 281 50 29 5 231 49 21 4 50 57 8 9 .5
≥65 years 227 41 23 4 204 43 17 4 23 26 6 7
Karnofsky performance status scale .6 1 .4
≥80% 463 83 49 9 400 85 35 7 63 73 14 16
<80% 45 8 3 1 35 7 3 1 10 11 0 0
Tumor extent* .048 .1 .8
pT1/2 336 60 27 5 306 65 22 5 30 35 5 6
pT3/4 172 31 25 4 129 27 16 3 43 49 9 10
Regional lymph node metastasis* .002 .02 .2
N0/pN0 477 84 42 8 418 88 33 7 59 68 9 10
pN1, pN2 31 6 10 2 17 4 5 1 14 16 5 6
Distant metastasis* .03 - -
No 435 78 38 7 - - - - - - - -
Yes 73 13 14 3 - - - - - - - -
Grade of malignancy .005 .2 .1
G1/2 430 77 35 6 386 82 30 7 44 51 5 6
G3/4 76 14 16 3 47 10 7 1 29 33 9 10
Histopathologic subtype .1 .8 .06
Clear-cell RCC 425 76 39 7 362 76 30 6 63 73 9 11
Papillary RCC 42 8 6 1 36 8 5 1 6 7 1 1
Chromophobe RCC 23 4 2 <1 23 5 1 <1 0 0 1 1
Spindle cell carcinoma 3 1 2 <1 1 <1 0 0 2 2 2 2
Collecting duct carcinoma 0 0 2 <1 0 0 1 <1 0 0 1 1
Unclassified RCC 15 3 1 <1 13 3 1 <1 2 2 0 0
Type of surgery .7 .7 .2
Radical nephrectomy 433 77 46 8 360 76 33 7 73 84 13 15
Partial nephrectomy 75 14 6 1 75 16 5 1 0 0 1 1

P values < .05 are shown in bold.

*

TNM 2002.

Three patients with tumors of unknown grade.

Clear-cell (conventional) RCC versus other types.