Figure 2.

hBPAG2 displayed normal ultrastructural localization in the epidermal BM of Tg skin. Post-embedding immunogold electron microscopy studies localized 5 nm gold particles staining hBPAG2 within the superior aspect of the lamina densa in human (a) and Tg (b) skin (arrows). This staining was consistent with that reported for this antiserum (Masunaga et al., 1997). Expression of hBPAG2 in Tg skin was somewhat less than that in human skin. There was no ectopic localization or aggregation of hBPAG2 in Tg skin. Anti-hBPAG2 antiserum showed no specific reactivity to the skin of a Wt mouse (c). HD, hemidesmosome; LL, lamina lucida; LD, lamina densa.