TABLE 1.
Results of the protection studiesa
Protein | No. (%) of animals that survived at:
|
|
---|---|---|
50×LD50 | 100×LD50 | |
P15 | 2 (33.3) | 0 (0) |
P33 | 3 (50) | 2 (33.3) |
P37 | 4 (66.6) | 3 (50) |
P49 | 6 (100) | 6 (100) |
Control | 0 (0) | 0 (0) |
Six mice were immunized with the four selected proteins for 3 weeks, followed by a single booster, before exposing them to two doses (50×LD50 and 100×LD50) of Salmonella serovar Typhimurium (wild). The results are for survival of animals after 14 days of bacterial challenge.