Schematic flowchart of the relationship of the ELISPOT assay results to empirical anti-TB therapy and the final classification of CNS TB. Of the total of 37 patients with suspected CNS TB, 2 patients gave indeterminate results by the PBMC ELISPOT assay. Data for the remaining 35 patients (11 with CNS TB plus 24 with not-active TB) were included in the final analysis of the PBMC ELISPOT assay. Of the 21 patients who agreed to additional CSF sampling, the CSF MCs from 5 patients gave indeterminate results by the ELISPOT assay. Thus, the CSF MC/PBMC ratio was assessed for the remaining 16 patients (4 with CNS TB plus 12 with not active TB) with suspected TB meningitis. a, data for 35 patients were included in the final analysis of the PBMC ELISPOT assay; b, data for 16 patients were included in the final analysis of the CSF MC ELISPOT assay. MRI, magnetic resonance imaging.