FIG. 1.

ROC analysis of discriminative LPA thresholds for the detection of CMV immunity with six CMV antigenic preparations and PHA. The data were derived from 36 CMV-seropositive and 27 CMV-seronegative healthy adults. The point closest to the upper left corner indicates the SI value associated with the highest paired sensitivity and specificity for the discrimination between CMV-seropositive and -seronegative individuals. The box around the threshold delineates the 95% joint confidence interval. The PHA ROC curve is shown as a typical example of a measurement lacking discriminative value. pos, positive; neg, negative; AUC, area under the curve.