TABLE 1.
Performance characteristics of six CMV antigens in three CMI assaysa
| Antigen | LPA
|
IFN-γ
|
IL-2
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. of samples | SI | Sensib | Specib | No. of samples | Concn (pg/ml) | Sensi | Speci | No. of samples | Concn (pg/ml) | Sensi | Speci | |
| Colorado | 55 | 5 | 91 (76, 98) | 95 (76, 100) | 16 | 3 | 100 (66, 100) | 100 (59, 100) | 16 | 3 | 78 (40, 97) | 71 (29, 96) |
| San Diego | 56 | 12 | 89 (73, 97) | 95 (76, 100) | 16 | 265 | 100 (66, 100) | 100 (59, 100) | 16 | 4 | 100 (66, 100) | 100 (59, 100) |
| UTMB | 55 | 15 | 86 (70, 95) | 95 (75,100) | 16 | 3 | 100 (66, 100) | 100 (59, 100) | 16 | 7 | 67 (30, 93) | 100 (59, 100) |
| BioWhittaker | 55 | 10 | 82 (65, 93) | 86 (64, 97) | 16 | 63 | 100 (66, 100) | 100 (59, 100) | 16 | 1 | 89 (52, 100) | 100 (59, 100) |
| gB | 30 | 3 | 85 (62, 97) | 90 (55, 100) | 13 | 3 | 88 (47, 100) | 100 (48, 100) | 13 | 20 | 38 (9, 76) | 100 (48, 100) |
| pp65 | 30 | 10 | 90 (63, 99) | 100 (69, 100) | 13 | 2 | 100 (63, 100) | 100 (48, 100) | 13 | 6 | 38 (9, 76) | 100 (48, 100) |
a
Abbreviations: Sensi, sensitivity; Speci, specificity.
b
The data represent percent sample estimates (95% confidence intervals).