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. 2008 Jun 25;15(9):1398–1409. doi: 10.1128/CVI.00479-07

TABLE 2.

Comparison of HIV plasma burden in subjects with and without CMV-specific CMI

Assay for CMI/antigen Responders' RNA copies/ml (no. of samples) Nonresponders' RNA copies/ml (no. of samples) P valuea Adjusted P valueb
LPA/Colorado 1,454c (39) 36,382 (53) <0.01 0.09
IFN-γ production/BioWhittaker 400 (29) 36,176 (28) <0.01 0.03
a

P values for the comparison of the HIV plasma titers of the CMI responders versus those of the nonresponders. The data show significantly lower HIV RNA titers in subjects with CMV LPA and inducible IFN-γ responses compared with those of subjects incapable of mounting responses.

b

P values for the comparison of the HIV plasma titers of the CMI responders versus those of the nonresponders with adjustment for CD4 cell numbers. The data indicate that the association between the HIV RNA copies/ml and CMV CMI response measured as IFN-γ production was maintained after adjustment for CD4 cell numbers

c

The data represent the median number of HIV RNA copies/ml of plasma in each group.