TABLE 2.
Induction of resistance of heteroresistant C. difficile isolates
| Isolate | Ribotype | Zone size (mm) after induction | MIC (mg/liter) determined by Etest after inductiona |
|---|---|---|---|
| 1 | R5 | 0 | 2 (256) |
| 2 | R14 | 0 | 1.5 (128) |
| 3 | R2 | 0 | 1 (64) |
| 4 | R2 | 0 | 0.5 (32) |
| 5 | R3 | 0 | 0.5 (32) |
| 6 | R4 | 0 | 0.5 (32) |
| 7 | R6 | 0 | 0.38 (16) |
| 8 | R1 | 0 | 0.125 (16) |
| 9 | R1 | 0 | 0.125 (16) |
| 10 | R1 | 0 | 0.125 (16) |
| 11 | R1 | 0 | 0.125 (16) |
| 12 | R1 | 0 | 0.125 (8) |
| 13 | R1 | 0 | 0.125 (8) |
| 14 | R1 | 0 | 0.125 (8) |
a
In each case, a resistant subpopulation (whose MICs are given in parentheses) was observed growing inside the inhibition zone of the Etest strip.