TABLE 3.
Differences in toxin gene profile of North American and European S. aureus isolates on univariate analysis
| Virulence factor and gene | No. (%) of isolatesa
|
||
|---|---|---|---|
| North American | European | Pb | |
| MRSA | 76 | 13 | |
| eta | 69 (91) | 4 (31) | <0.001 |
| pvl | 42 (55) | 0 | <0.001 |
| seb | 63 (83) | 4 (31) | <0.001 |
| sec | 11 (14) | 6 (46) | 0.015 |
| tst | 48 (63) | 13 (100) | 0.008 |
| arcA | 25 (33) | 0 | 0.016 |
| MSSA | 119 | 22 | |
| eta | 100 (84) | 8 (36) | <0.001 |
| pvl | 26 (22) | 0 | 0.014 |
| seb | 96 (81) | 1 (5) | <0.001 |
No significant differences were observed among North American and European isolates for the following genes: bbp, clfA, clfB, cna, ebpS, fnbA, fnbB, map (eap), sdrC, sdrD, sdrE, spa, etb, hlg, sea, sed, see, seg, seh, sei, sej, agr I to IV, chp, efb, icaA, V8, and SCCmec I to IV (MRSA) and bbp, clfA, clfB, cna, ebpS, fnbA, fnbB, map (eap), sdrC, sdrD, sdrE, spa, etb, hlg, sea, sec, sed, see, seg, seh, sei, sej, tst, agr I to IV, chp, efb, icaA, and V8 (MSSA; SCCmec and arcA analyses were not performed for MSSA isolates). The percentages refer to the percentage of patients within each S. aureus subset with the indicated virulence gene.
As determined by the Fisher exact test; all P values shown in this table (referring to a comparison of values for North American and European isolates) are statistically significant with an FDR of <20%.