TABLE 3.
Summary of lipoChFP inner membrane retention signals
| Sorting signala | Lipoproteinb | Protein function | P. aeruginosa IM retention rulec | Localization in P. aeruginosa | Localization in E. coli |
|---|---|---|---|---|---|
| CSFP | PA4756, OmlA | Maintain cell envelope integrity | None | OM | OM |
| CDFP | OmlA +2 variant | None | OM | IM | |
| CAST | PA4876, OsmE | Osmotic shock response | None | OM | OM |
| CAST | PA5310 | Lipid metabolism | None | OM | OM |
| CDSQ | PA3262 | Peptidyl-prolyl cis-trans isomerase | Asp+2 | IM | IM |
| CGKS | PA0425, MexA | RND efflux membrane fusion protein | Lys+3 Ser+4 | IM | OM |
| CGKS | PA2321 | Glucokinase | Lys+3 Ser+4 | IM | OM |
| CFNS | Not present | Non-aspartate+2 | IM | IM | |
| CGNG | PA3677 | RND efflux membrane fusion protein | Non-aspartate+2 | IM | IM |
| CGGG | PA5041, PilP | Type IV pilus assembly | Novel | IM | OM |
| CGGG | PA5414 | Hypothetical protein | Novel | IM | OM |
| CKVE | PA1723, PscJ | Type III secretion machinery | Novel | IM | OM |
| CQGS | PA1812, MltD | Lytic murein transglycosylase D | Novel | IM | OM |
| CGDD | PA4370, IcmP | Metalloprotease | Novel | IM | IM |
a
The first four amino acids of the mature N terminus from predicted P. aeruginosa lipoproteins in the C +2 +3 +4 region.
b
The PA identification number and protein name, if available, which contains the lipoprotein sorting signal listed to the left.
c
IM, inner membrane; OM, outer membrane.